BMIC — Routine Bacterial AST
The BMIC strip is BioMaxima's broad-panel gradient diffusion MIC test strip for routine bacterial antimicrobial susceptibility testing. It covers the major antibacterial agent classes required for everyday clinical microbiology AST — penicillins, cephalosporins, carbapenems, aminoglycosides, fluoroquinolones, tetracyclines, macrolides, glycopeptides, and more.
Each strip is manufactured using BioMaxima's patented biomedical composite carrier technology — a layered composite with a fibrous synthetic polymer fibre carrier layer developed in partnership with Arctic Paper Kostrzyn S.A. This patented substrate delivers precise, reproducible antibiotic diffusion across 15 two-fold dilution steps, producing a stable, continuous exponential concentration gradient in the agar.
BMIC strips are placed on Mueller-Hinton agar inoculated with the test organism. After incubation at 35 ± 1°C for 16–20 hours, the MIC is read in µg/mL directly at the point where the bottom of the teardrop-shaped inhibition ellipse intersects the strip's graduated scale. No serial dilution preparation is required.
Results are interpreted using the current annual edition of EUCAST Clinical Breakpoint Tables or CLSI M100, classifying isolates as S (susceptible), I (susceptible at increased exposure), or R (resistant).
Why BioMaxima BMIC Strips
Developed through university research partnerships and a patented composite substrate — delivering consistent, reproducible gradient diffusion AST.
Biomedical Composite Carrier
BMIC strips use a patented biomedical composite carrier layer reinforced with synthetic polymer fibres — developed in collaboration with Arctic Paper. This substrate delivers precise, consistent antibiotic diffusion across all 15 two-fold dilution steps with exceptional lot-to-lot reproducibility.
University-Validated Technology
The MIC test platform was developed through a five-year research programme (2017–2022) in collaboration with UMCS Lublin (Departments of Genetics and Microbiology, and Biochemistry) and the Medical University of Lublin — with two patent applications filed as a result.
EUCAST & CLSI Aligned
BMIC gradient diffusion methodology follows the same principles as EUCAST and CLSI broth microdilution reference methods. Results are interpreted using current EUCAST Clinical Breakpoint Tables or CLSI M100 for susceptible (S), intermediate (I), or resistant (R) classification.
No Serial Dilution Required
Unlike broth microdilution, BMIC strips require no preparation of antibiotic dilution series. A single strip placed on an inoculated agar plate delivers the full 15-step dilution gradient — reducing preparation time and minimising the risk of dilution error.
Standard Laboratory Infrastructure
BMIC testing requires only standard microbiology laboratory equipment — an incubator, agar plates, and a turbidity standard. No specialist analyser, reader, or additional reagent system is required for routine application.
Supports AMR Stewardship
Quantitative MIC values in µg/mL support PK/PD-guided dose optimisation, enabling clinicians and stewardship pharmacists to tailor antibiotic regimens — supporting responsible antimicrobial use and contributing to the reduction of antimicrobial resistance.
Representative BMIC Panel — Antibiotic Classes
The BMIC range covers over 100 antibacterial agents across all major antibiotic classes for routine clinical bacterial AST. Individual strips are available for each agent. Contact Advanced Biotech for the current full agent list and catalogue numbers.
Pack Sizes
BMIC strips are available in three pack sizes to suit laboratory throughput. Each strip is individually packaged. Contact Advanced Biotech for pricing, catalogue numbers, and current availability.
Suitable for low-throughput testing, evaluation, or infrequent use of specific agents. Individually packaged strips maintain stability and reduce waste.
EnquireStandard pack size for routine clinical laboratory use. Cost-effective for regular AST workflows without requiring bulk storage of high-volume packs.
EnquireHigh-volume pack for reference laboratories, high-throughput clinical settings, or institutions requiring bulk supply of frequently tested agents.
EnquireTechnical Specifications
Key technical parameters for the BMIC gradient diffusion MIC test strip.
| Parameter | Specification |
|---|---|
| Product name | BMIC MIC Test Strip — Broad-Panel Bacteriology |
| Platform | Gradient diffusion minimum inhibitory concentration (MIC) test |
| Target organisms | Aerobic and facultatively anaerobic bacteria (routine clinical isolates) |
| Antibiotic coverage | Broad panel — major antibacterial agent classes (contact Advanced Biotech for current full list) |
| Dilution range | 15 two-fold dilution steps — factory-calibrated continuous gradient |
| Test medium | Mueller-Hinton agar (standard formulation, EUCAST/CLSI specification) |
| Inoculum | 0.5 McFarland turbidity standard — direct colony suspension method |
| Incubation temperature | 35 ± 1°C |
| Incubation duration | 16–20 hours (refer to IFU for organism-specific conditions) |
| MIC reading | µg/mL — read at ellipse/strip intersection point |
| Breakpoint standards | EUCAST Clinical Breakpoint Tables (current edition) / CLSI M100 |
| Pack sizes | 10, 30, 100 tests — individually packaged strips |
| Storage | 2–8°C (refer to product label and IFU) |
| Regulatory category | Class 2 IVD — for in vitro diagnostic use only |
| ARTG number | 524158 |
| Manufacturer | BioMaxima S.A., Lublin, Poland |
| Australian distributor | Advanced Biotech Pty Ltd |
Downloads
Instructions for Use, Safety Data Sheet, and regulatory documentation for BMIC MIC Test Strips.
Order BMIC or Request Technical Information
Contact Advanced Biotech Pty Ltd for pricing, catalogue numbers, pack sizes, and availability of BMIC MIC Test Strips in Australia.